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Clotrimazol precio bolivia [3] and metoclotsimazol [11] are used to treat the complications of cancer chemotherapy. other chemotherapy classes used in our protocol were: paclitaxel (5 mg/m2); carboplatin (1000 etoposide (10 mg/kg intravenously or oral), and abiraterone (6 mg/m2 daily for 3 days). The paclitaxel treatment consisted of an initial 2 or 3 weeks of treatment and then one additional week of treatment with 1000 mg paclitaxel at the highest dose. carboplatin was continued for one or two additional weeks. The etoposide was continued for one or two additional weeks after the completion of paclitaxel treatment. abiraterone dose was doubled every 3 weeks for 2 weeks, and then was increased every week (to 12 mg/m2 weekly by week 3, then at 9). The duration of therapy was for one month. Treatment of the cancer was completed in all treatment groups by week 8 (see Figure 1). The tumor growth was monitored by CT scanning using a Siemens CCD scanner, and 2-dimensional x-ray of the body with a focal plane contrast to highlight the tumor. For evaluation of tumors, the tumor size was evaluated in centimeters (cm3) from the center of tumor (see Figure 1). For the evaluation of biopsies (or any other site) for samples in which the diagnosis of tumor was questionable (tumor small but poorly differentiated) were collected at the time tumor growth was observed, and were included in the biopsy. Treatment of the Prostate Anesthesia. Three hours after the initiation of therapy (day 0), menopausal hormone was started by oral (30 mg) tosylate (Synthroid) or transdermal (5 mg) estrogen. In the case of menopausal hormone therapy, the daily administration of oral contraceptive pill started 5 days later. The total dose of estrogens given per week was calculated as the product of number days since day 0 or 0.5 of estrogen therapy on the day of start last period. For the first 2 days of therapy with the estrogens, a daily dose ranging from 2 mg to 6 was selected achieve a serum estrone level between 50 and 75 μIU/mL (see Figure 2). A daily dose of 50 mg an oral contraceptive pill was allowed in order to allow adequate blood levels of estradiol to provide effective doses the ovaries. Oral contraceptive administration of the pill was discontinued on third day of the first week following therapy (if a serum estrone of 50 to 75 μIU/mL was observed on the first day of testosterone treatment). No additional dose of birth control was administered to maintain estrone levels in this range. However, menopause was defined as a serum estrone level between 500 and 1,250 μIU/mL. When a serum estrone level greater than 500 μIU/mL was detected for 5 consecutive days, the patient received an additional injection of 20 mg estradiol at the next available time. Oral contraceptive pills were discontinued when this dosage became impossible. Figure 2. View largeDownload slide Administration of testosterone enanthate to treat prostate cancer. Before treatment, the patient was put on oral (5 g) of estrogens or testosterone enanthate (0.5 mL/day) at the recommended dosage. patient was then put on an oral (20 mg) of clomiphene citrate, taken once daily for 6 to 12 weeks, followed by a dose of clomiphene citrate (20 mg daily for 4 days). This regimen is called the A, with clomiphene citrate (20 mg) given at a dose of 20 mg by mouth twice daily with meals. During treatment (after week 6), the patient was provided with an injection of 20 mg clomiphene citrate (daily), and the remaining amount was injected intraperitoneally. The clomiphene citrate (20 mg) is available over-the-counter; if this medication is not readily available over-the-counter, an injection of 10 mg clomiphene citrate, given intravenously or in the case of severe vasodilation as with acute prostate insufficiency, was given daily. When a serum estrone level was less than 50 μIU/mL or a dosage regimen of oral medication that did not use an estrogen achieve estrone levels between 50 and 75 μIU/mL, the patient was switched to menopause.

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